开发一个基于虚拟现实的干预社区行走中风后:一个综合的知识翻译方法
Myriam Villeneuve1,2, Tatiana Ogourtsova1,2, Anne Deblock-Bellamy3,4,5
1School of Physical and Occupational Therapy, McGill University, Montreal, Canada.
Disability and rehabilitation
|November 3, 2023
概括
这项研究探讨了临床医生和中风幸存者对社区步行虚拟现实 (VR) 干预的反. 这些发现将为未来的有效性和实施研究完善VR工具.
科学领域:
- 康复技术 康复技术 康复技术
- 医疗保健中的虚拟现实
- 神经康复疗法 神经康复疗法
背景情况:
- 虚拟现实 (VR) 干预措施有望改善功能移动性.
- 开发有效的VR工具需要了解用户的观点和优化功能.
- 社区步行是中风幸存者的独立性的关键结果.
研究的目的:
- 开发基于虚拟现实 (VR) 的干预方案,以社区步行需求为目标.
- 为了收集临床医生和中风幸存者的反关于一种新的VR干预.
- 确定基于VR的康复的最佳特征并解决基于VR的康复的潜在挑战.
主要方法:
- 两个临床医生重点小组探索了VR干预的最佳特征,支持需求和感知因素.
- 卒中幸存者和临床医生与VR干预互动,填写接受度和感知问卷.
- 脑卒中参与者使用经过验证的尺度对感知到的努力,存在和网络疾病进行了评价.
主要成果:
- 确定的关键因素包括患者的资格,任务的复杂性,认知刺激,参与度和治疗目标对齐.
- 临床接受度分数在28-42 (最大56) 之间;中风参与者的分数在43-52之间.
- 卒中幸存者报告说中等的努力,高的存在,和最小的网络病.
结论:
- 早期发现将通过解决已识别的因素和结合最佳特征来精细化VR干预.
- 这种代的开发方法旨在提高VR工具适合未来的有效性和实施研究.
- 以用户为中心的设计对于开发成功的基于VR的康复技术至关重要.
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Translation Produces the Building Blocks of Life
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Translation
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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Translation
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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Improving Translational Accuracy
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are called the...
Translation Produces the Building Blocks of Life
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