在I-STOP-AFIB随机试验中,先前的夜间睡眠质量和心房动情节
Christopher X Wong1, Madelaine Faulkner Modrow2, Kathi Sigona3
1Division of Cardiology, University of California-San Francisco, San Francisco, California, USA.
JACC. Clinical electrophysiology
|November 3, 2023
概括
睡眠质量差会增加第二天心房动 (AF) 发作的风险. 睡眠持续时间和质量的恶化与较长的AF发作相关,这表明睡眠是一个可修改的触发因素.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 慢性睡眠障碍与新发动的心房动 (AF) 有关.
- 睡眠质量差对引发AF发作的急性影响尚不清楚.
研究的目的:
- 调查夜间睡眠质量与离散心房动 (AF) 发作事件的直接风险之间的关系.
- 为了确定睡眠质量是否起到AF的急性触发作用.
主要方法:
- 利用了I-STOP-AFIB试验中的419名患者的数据,收集了15755个患者日的信息.
- 患者自我报告每日睡眠质量,AF发作,并接受了每日基于智能手机的移动心电图监测.
- 统计分析对每周一天进行调整,以评估睡眠质量和AF风险之间的关联.
主要成果:
- 睡眠质量差与第二天自己报告的AF事件的几率增加15%有关 (OR:1.15,P < 0.0001).
- 观察到一种剂量-反应关系,较差的睡眠与较长的AF发作有关 (每种恶化睡眠类别的睡眠时间长16分钟,P < 0.001).
- 睡眠质量恶化和移动心电图确认的AF事件之间没有发现显著的关联,可能是由于统计能力有限.
结论:
- 睡眠质量差与自我报告的AF发作风险的立即增加有关.
- 睡眠质量似乎是AF短期风险的潜在可修改触发因素.
- 需要进一步的研究来确认与客观测量AF事件的关联.
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