饮食中的摄入量和发生2型糖尿病的风险
Xuan Wang1, Hao Ma1, Minghao Kou1
1Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
较高的盐摄入量,即经常添加盐到食物中,与患2型糖尿病 (T2D) 的风险增加有关. 这项研究强调了饮食习惯与T2D发病率之间的关联.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 代谢性疾病研究研究
背景情况:
- 长期饮食摄入在2型糖尿病 (T2D) 中的作用仍然不完全理解.
- 饮食习惯,如将盐添加到食物中,可以作为持续消费的代理.
研究的目的:
- 调查食品添加盐的频率与发生T2D的风险之间的关联.
- 探索这种关系中的潜在调解因素.
主要方法:
- 分析了402,982名英国生物库参与者 (2006-2010年) 在基线没有主要慢性疾病.
- 随访时间平均为11.9年,记录了T2D病例事件.
- 使用考克斯比例危险模型进行统计分析,并根据相关共变量进行调整.
主要成果:
- 增加添加盐的频率与较高的T2D风险相关 (HRs从1.11到1.28不等).
- 没有发现盐添加频率与高血压或其他共同变量之间的显著相互作用.
- 身体质量指数 (33.8%),腰与部比率 (39.9%) 和C反应蛋白 (8.6%) 部分介导了这种联系,身体脂肪质量是关键的驱动因素.
结论:
- 将盐添加到食品中的频率更高与T2D的风险增加有关.
- 这一发现表明,盐味偏好和长期摄入与T2D发展有关.
- 针对盐摄入量的干预措施可能在T2D预防中发挥作用.
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