在用乙烯乙醇共聚合物 (EVOH) 进行前列腺栓塞时发生的非目标栓塞事件
Jacques Sédat1, Paolo Arnoffi2, Florent Poirier2
1Service de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France. jsedat@yahoo.fr.
CVIR endovascular
|November 3, 2023
概括
使用乙烯乙醇共聚合物 (EVOH) 的前列腺动脉栓塞 (PAE) 是对良性前列腺增生 (BPH) 的安全有效治疗方法. 这项研究发现PAE与EVOH导致显著的症状改善,最小的非目标栓塞 (NTE).
科学领域:
- 干预性放射学 干预性放射学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 血管外科 血管外科
背景情况:
- 良性前列腺增生症 (BPH) 导致下泌尿道症状 (LUTS).
- 前列腺动脉栓塞 (PAE) 是BPH的另一种治疗方法.
- 乙烯乙醇共聚物 (EVOH) 是一种用于PAE的栓塞剂.
研究的目的:
- 在使用EVOH的PAE期间评估非目标栓塞 (NTE).
- 评估PAE与EVOH的安全性和有效性,用于与BPH相关的LUTS.
主要方法:
- 对10名BPH相关的LUTS患者进行前性研究,这些患者接受了EVOH的PAE.
- 在X射线指导下,使用微导管双边注射EVOH.
- 盆腔CT扫描评估了栓塞前后的NTE.
- 副作用和国际前列腺症状评分 (IPSS) 和生活质量 (QoL) 评分被监测了3个月.
主要成果:
- 带有EVOH的PAE在技术上是成功的,在10个患者中,有9个是成功的.
- 3个月后,IPSS (平均-11.5分) 和QoL (平均-3.40分) 的得分显著改善.
- 只有一个患者经历了无症状的肌肉NTE;没有报告术后疼痛.
结论:
- 带有EVOH的PAE是一种安全有效的治疗BPH相关的LUTS.
- 该程序与NTE的低率和没有术后疼痛有关.
- 建议进行进一步的比较研究,并进行更长的随访.
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