乌干达老年人的认知能力:在前性人口研究中,与死亡率的相关性,随着时间的推移的趋势和相关性
Josephine E Prynn1, Calum Davey2, Daniel Davis3
1Institute of Cardiovascular Sciences, University College London, London, United Kingdom.
PLOS global public health
|November 3, 2023
概括
乌干达老年人的认知能力下降与年龄和低教育程度有关,但与艾滋病毒或中风无关. 需要进一步的研究,以了解临床痴呆症在公共卫生规划中的表现.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 老年学是一门学科.
背景情况:
- 痴呆症在撒哈拉以南非洲是一个日益关注的问题,但流行病学数据和特定区域的风险因素很少.
- 该地区的高中风发病率和艾滋病毒患病率可能与世界其他地区不同地影响痴呆症风险因素.
- 了解非洲老年人的认知健康对于开发有效的痴呆症护理公共卫生策略至关重要.
研究的目的:
- 研究撒哈拉以南非洲老年人认知的流行病学.
- 检查与认知衰退和这一群体的护理需求相关的因素.
- 探索认知得分与死亡率之间的关系.
主要方法:
- 利用了来自老年人福祉研究的数据,这是乌干达 (2009-2019) 开放的队列,有811名50岁以上的参与者.
- 在四个波段中收集了社会人口统计,健康和认知数据 (口头回忆,数字跨度,口头流利).
- 采用随机效应建模来分析基线认知,认知变化,护理需求和死亡率之间的关联.
主要成果:
- 较低的基线认知分数与年龄较大,教育程度较低,社会经济地位较低和极端的BMI有关.
- 认知得分随着年龄的增长而下降得更快,独立于心血管疾病或基线HIV状况.
- 认知分数较低的个体需要更多的日常生活活动帮助,尽管在认知分数范围内的死亡率相似.
结论:
- 确定了与乌干达老年人认知能力下降相关的关键人口和社会经济因素.
- 认知能力下降的速度随着年龄的增长而加快,但在这个群体中,认知能力下降与艾滋病毒或心血管疾病没有直接联系.
- 对临床痴呆症呈现的进一步调查对于为该地区的公共卫生规划和干预提供信息至关重要.
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