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Updated: Jul 11, 2025

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触发内源Z-RNA传感器通过ZBP1-依赖性亡来进行抗瘤治疗

Tao Yang1, Guodong Wang1, Mingxiang Zhang2

  • 1CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Cell reports
|November 3, 2023
PubMed
概括

氧化应激诱导宿主细胞中Z-RNA的形成,Z-RNA结合蛋白1 (ZBP1) 在应激颗粒中感知到这种Z-RNA结合蛋白1 (ZBP1),从而引发亡. 这种机制通过促进抗瘤细胞死亡来增强化疗效.

关键词:
CP: 癌症 癌症 癌症CP: 细胞生物学 细胞生物学这就是Z-RNA.在 ZBP1 中,ZBP1 是尸体的死亡和死亡.氧化应激是一种氧化应激.应力颗粒的压力颗粒瘤化疗 瘤化疗

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