术后成像监测策略的成本效益与非功能性垂体腺瘤的治疗意图切除后的切除
Lisa Caulley1,2,3,4, Stijntje W Dijk5,6, Eline Krijkamp5
1Departments of1Otolaryngology-Head and Neck Surgery.
Journal of neurosurgery
|November 3, 2023
概括
在垂体腺瘤切除后进行个性化MRI监测是具有成本效益的. 与年度或逐渐监测相比,这种策略提供了更好的结果和价值,优化了患者护理.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 卫生经济学 卫生经济学
背景情况:
- 非功能性垂体腺瘤 (NFAs) 需要有效的术后监测.
- 目前的监测策略各不相同,影响患者的长期结果和医疗保健成本.
研究的目的:
- 确定NFA切除后最具成本效益的成像监测策略.
- 为了比较年度,逐渐和个性化的MRI监测协议.
主要方法:
- 一个个别级的状态过渡微型模拟模型模拟了终身成本和质量调整寿命年 (QALYs).
- 模拟了三个策略:年度,逐渐 (5年一次,然后两年一次) 和个性化 (基于MRI发现).
- 关于过渡概率,公用事业和成本的数据是从已发表的文献中得出的,并进行了折扣.
主要成果:
- 由于成本较高和QALY较低,年度监测主要采用了逐渐缩小和个性化策略.
- 与逐渐缩小的监控相比,个性化监控产生了额外的0.1 QALY,成本为1298美元.
- 个性化监控的增量成本效益比 (ICER) 为11,793美元/QALY,最佳的概率为79%.
结论:
- 个性化MRI监测是NFA切除后患者的成本有效策略.
- 这种方法优化了资源配置,同时最大限度地提高了患者的健康结果.
- 该模型对术后MRI变化和MRI成本的敏感性突出了实施的关键因素.
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