[翻译文章] 免疫疗法和针对性治疗在患有晚期黑色素瘤和V600 BRAF突变的患者:哪一个先?
D Moreno-Ramírez1, A Fernández-Orland1, L Ferrándiz1
1Unidad de Melanoma, Servicio de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario Virgen Macarena, Seville, Spain.
Actas dermo-sifiliograficas
|November 3, 2023
概括
系统性治疗,如免疫疗法和向治疗,可以改善晚期黑色素瘤的存活率. 一个算法有助于指导BRAF突变黑色素瘤的治疗决策,平衡疗效和毒性.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 医学研究 医学研究
背景情况:
- 先进的黑色素瘤治疗已经与免疫疗法和向治疗一起发展.
- 在50%的黑色素瘤患者中存在BRAF突变,影响治疗选择.
- 系统疗法的最佳测序需要考虑药物,瘤和患者因素.
结论:
- 需要一个结构化的方法来优化全身疗法测序.
- 提出的算法有助于临床医生在免疫疗法和向治疗之间做出选择.
- 个性化治疗策略对于改善晚期黑色素瘤的结果至关重要.
关键词:
辅助性治疗是一种辅助性治疗.这是一种抗CTLA4的药物.这是一种抗PD1的药物.BRAF 抑制剂的使用BRAF-MEK 抑制剂的使用这是一种CTLA4抑制剂.免疫治疗是一种免疫疗法.抑制剂的 BRAF 的抑制剂.的抑制剂 BRAF-MEK.免疫疗法是一种免疫疗法.黑色素瘤是一种黑色素瘤.新辅助疗法是一种新辅助疗法.这是一种PD1抑制剂.有针对性的治疗.有针对性的疗法.作为辅助治疗的方法.这是一种新型辅助治疗.更多相关视频
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