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Updated: Jul 11, 2025

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补充替代途径决定了抗中性粒细胞体抗体 (ANCA) 相关的血管炎的疾病易感性和严重程度

Laura Lucientes-Continente1, Gema Fernández-Juárez2, Bárbara Márquez-Tirado1

  • 1Department of Immunology, Ophthalmology and Otorhinolaryngology (ENT), Complutense University, Madrid, Spain; Area of Chronic Diseases and Transplantation, Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.

Kidney international
|November 3, 2023
PubMed
概括

补充替代途径 (AP) 组件的遗传变异和血水平影响抗中性粒细胞质抗体相关血管炎 (AAV) 的易感性和严重程度. 补充因子H相关蛋白1 (FHR-1) 的平衡至关重要,这表明它是治疗点.

关键词:
在ANCA-血管炎.FH FH FH 的意思是在FHRs中,FHRs是最重要的.另一个替代路径路径.补充补充补充补充补充补充补充.

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