坚持健康的睡眠模式和新出现的急性损伤
Xiaoqin Gan1, Panpan He1, Ziliang Ye1
1Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, China.
Sleep health
|November 3, 2023
概括
健康的睡眠模式显著降低了新发症急性损伤 (AKI) 的风险. 这种关联甚至适用于具有病遗传倾向的个体,强调睡眠.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 急性损伤 (AKI) 是一个具有多因素原因的重大临床问题.
- 睡眠障碍越来越多地被认为是各种健康结果的潜在贡献者.
- 了解睡眠等可修改因素对于AKI预防策略至关重要.
研究的目的:
- 检查个人睡眠特征和整合健康睡眠模式与新发性AKI发生率之间的潜在关系.
- 评估遗传倾向是否影响睡眠模式与AKI风险之间的关联.
主要方法:
- 利用了来自375,216名参与者 (年龄在37-73岁之间) 的英国生物库数据.
- 根据睡眠时间,时间类型,失眠,打和白天嗜睡,开发了健康睡眠评分 (0-5分).
- 使用ICD-10代码N17定义的新发病的AKI,通过多个数据源在中位数12.0年的随访中确定.
主要成果:
- 健康睡眠得分与AKI风险相反相关 (HR,0.95;95% CI,0.93-0.97).
- 最佳的睡眠时间 (7-8小时),早期的时刻型,不经常的失眠和白天不睡觉与较低的AKI风险有关.
- 这种联系在非糖尿病患者中尤为强烈,并没有受到 AKI 的遗传倾向或估计的球过率的显著改变.
结论:
- 健康的睡眠模式是预防新发症急性损伤的重要保护因素.
- 这些发现强调了促进健康的睡眠习惯对脏健康的重要性,无论遗传风险因素如何.
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