不同类型的屏幕时间,体力活动,以及发生的痴呆症,帕金森病,抑郁症和多病症状态
Hanzhang Wu1,2,3, Yeqing Gu4, Wenxiu Du1,2
1School of Public Health of Tianjin, University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin, 301617, China.
概括
适度使用电脑可能会降低痴呆症,帕金森病 (PD) 和抑郁症的风险,而大量看电视会增加风险. 用身体活动取代屏幕时间,可以提供对这些神经疾病的保护性益处.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 过度的屏幕时间与痴呆症,帕金森病 (PD) 和抑郁症患病率增加有关,尽管研究结果不一致.
- 这项研究解决了对屏幕时间对大脑结构和神经疾病发病率的影响的前性调查的需要.
研究的目的:
- 为了前性地研究不同类型的屏幕时间 (电视,电脑) 和大脑结构之间的关联.
- 评估痴呆症,PD,抑郁症的发病率及其与屏幕时间相关的多病性.
- 利用MRI数据探索这些关联的神经生物学基础.
主要方法:
- 利用英国生物库的数据,从473184名参与者最初没有痴呆症,PD和抑郁症.
- 收集了39652名参与者的自我报告的屏幕时间数据 (电视观看,电脑使用) 和MRI数据.
- 采用Cox比例危险回归和多重线性回归模型来分析关联.
主要成果:
- 适度的电脑使用与痴呆症,PD,抑郁症和多病症风险降低相关.
- 较长的电视观看时间与痴呆症,PD,抑郁症及其多病症的风险增加有关.
- 适度的电脑使用显示出与海马体体积的积极关联和与白质超强度体积的负面关联,而大量的电视观看与海马体积的减少有关.
结论:
- 适度使用电脑与痴呆,PD和抑郁症的风险较低有关,而增加电视观看则会增加风险.
- 屏幕时间影响疾病风险,可能是通过大脑结构的改变.
- 将屏幕时间替换为体力活动,特别是强度炼,可显著降低这些神经疾病的风险.
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