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肺切除后咳的危险因素
Yongming Wu1,2, Wenpeng Song1,2, Dongmei Zhu3,4
1Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
World journal of surgical oncology
|November 4, 2023
概括
这次元分析确定了肺切除后咳的关键风险因素. 女性性别,手术前咳,右肺手术,叶切除术,特定淋巴结解剖,紧器关闭和酸性反流增加咳风险,而年轻的年龄可能是保护性的.
科学领域:
- 胸部外科手术 胸部外科手术
- 肺部病理学 肺部病理学
- 医学研究 医学研究
背景情况:
- 手术后咳是肺切除后的一个常见并发症.
- 识别风险因素对于改善患者的治疗结果和制定有针对性的干预措施至关重要.
研究的目的:
- 进行元分析,以确定肺切除后与咳相关的独立风险因素.
- 综合来自多项研究的证据,以全面了解术后咳病因.
主要方法:
- 在主要数据库 (PubMed,Embase,Web of Science等) 进行了系统的文献搜索. 在2022年11月之前.
- 在分析中包括了19项涉及4755名患者的研究.
- 使用Q测试和I2统计来评估统计异质性,使用逆方差方法组合的几率比率 (OR).
主要成果:
- 手术后咳的发生率在21.1%至55.8%之间.
- 确定的独立风险因素包括:年轻的年龄 (保护性),女性性别,手术前咳,右叶手术,叶叶切除术,下下和中下淋巴结剖析,支气管茎的关闭,周围淋巴结切除,以及术后的酸性反流.
结论:
- 几个因素显著增加了肺切除后发生咳的风险.
- 手术前的咳,特定的手术技术 (淋巴切除术,淋巴结解剖,合器关闭) 和术后的酸倒流都是强烈的预测因素.
- 年龄较小似乎是防止患上术后咳的保护因素.
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