屠宰场废水中的抗生素耐药性和加强的抗菌蓝光技术用于废水净化污染
Xiaoyu Cong1, Peter Krolla1, Umer Zeb Khan2
1Microbiology/Molecular Biology Department, Institute of Functional Interfaces (IFG), Karlsruhe Institute of Technology (KIT), Hermann von Helmholtz Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
Environmental science and pollution research international
|November 4, 2023
概括
屠宰场的废水含有ESKAPE细菌和抗生素耐药性基因 (ARG). 抗菌剂BlueLight (aBL) 含有氨酸有效地减少了这些污染物,显示出对废水处理的前景.
科学领域:
- 环境微生物学环境微生物学
- 抗微生物耐药性 抗微生物耐药性
- 废水处理技术 废水处理技术
背景情况:
- 屠宰场的废水是ESKAPE病原体和抗生素耐药性基因 (ARG) 的重要来源.
- 传统的废水处理方法可以部分减少,但不能消除这些污染物.
- 需要新兴技术来应对废水中抗菌素耐药性的挑战.
研究的目的:
- 在家禽和猪屠宰场废水中量化ESKAPE细菌和ARG.
- 评估传统处理方法在减少这些污染物的有效性.
- 调查抗微生物BlueLight (aBL) 与氨酸结合的潜力,作为一种新的废水处理方法.
主要方法:
- 用分子生物学方法量化了ESKAPE细菌和14种ARG.
- 在传统的生物或先进的氧化处理之前和之后,分析了废水样本.
- 在对ESKAPE细菌和真实废水中测试了带有和没有氨酸光敏感剂的aBL (420-480nm LED) 的有效性.
主要成果:
- 原始屠宰场废水中含有高水平的ESKAPE细菌和临床相关的ARG,包括对储备抗生素的抗生素.
- 传统的治疗方法可以减少,但不能消除细菌和ARG度.
- aBL显示对ESKAPE细菌的有效性有所变化,氨酸显著增强了这种有效性,特别是对于Klebsiella pneumoniae和Enterococcus faecium.
结论:
- 屠宰场的废水存在ESKAPE细菌和ARG的风险,即使经过标准处理.
- 抗微生物BlueLight,特别是与氨酸光敏感剂结合使用时,显示出在废水中禁用这些耐药细菌和基因的巨大潜力.
- 这种组合疗法为先进的废水处理提供了一个有希望的途径,以减轻抗菌素耐药性的传播.
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