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Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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软和灵活的生物电子微系统用于电子控制的药物输送.

Massimo Mariello1, Ismail Eş1, Christopher M Proctor1

  • 1Department of Engineering Science, Institute of Biomedical Engineering (IBME), University of Oxford, Oxford, OX3 7DQ, UK.

Advanced healthcare materials
|November 4, 2023
PubMed
概括

电子控制药物输送 (ECDD) 通过克服生物障碍,提供精确,可适应的治疗. 这项技术利用软,灵活的生物电子系统来提高医疗器械的有效性和患者的治疗结果.

关键词:
生物电子学 生物电子学药物输送是药物输送的过程.电子控制 电子控制 电子控制电光泳是一种电光泳.灵活性 灵活性 灵活性植入式设备可以植入设备.可摄入的设备可以被摄入.微系统的微系统.软生物电子系统软生物电子系统可穿戴设备可穿戴设备.

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科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 有针对性的药物输送旨在提高治疗效果,并最大限度地降低全身毒性.
  • 目前的药物输送系统在生物相容性,组织融合和克服生物障碍方面面临挑战.
  • 精准医学的进步需要新的材料和方法来控制治疗的管理.

研究的目的:

  • 审查最近在软,灵活的生物电子微系统中取得的突破,用于电子控制药物输送 (ECDD).
  • 提供ECDD操作模式,材料,电子接口和表征技术的概述.
  • 讨论ECDD在医疗器械中的应用,未来前景和挑战.

主要方法:

  • 对ECDD软,灵活和可适应的生物电子微系统的最新文献的审查.
  • 分析操作模式,材料工程策略和电子接口.
  • 探索可穿戴,可吞和可植入设备中的表征技术和应用.

主要成果:

  • 作为一种精确的方法,ECDD的出现,用于校准的药物输送,并具有空间和时间控制.
  • 开发软,灵活的生物电子微系统,使药物释放具有适应性.
  • 确定关键材料,接口和表征方法,这些对ECDD系统开发至关重要.

结论:

  • ECDD系统代表了精准医学的重大进步,为药物管理提供了更好的控制.
  • 软,灵活的生物电子微系统对于开发下一代ECDD设备至关重要.
  • 需要进一步的研究来应对挑战,并充分实现ECDD在临床应用中的潜力.