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用四种和八种气味进行嗅觉训练:与临床测试和嗅觉球体体积的比较

Sotiria Genetzaki¹, Vasilios Nikolaidis¹, Konstantinos Markou¹

¹2nd ORL Academic Department, Aristotle University, Thessaloniki, Greece.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|November 4, 2023

概括

用8种气味进行的嗅觉训练 (OT) 与4种气味相比,对于后感染性嗅觉功能障碍 (PIOD) 的有效性没有显著差异. 然而,8气味方案改善了患者长期嗅觉再培训的坚持.

科学领域:

神经学神经学
耳鼻喉科耳鼻喉科耳鼻喉科
医学研究医学研究

背景情况:

感染后嗅觉功能障碍 (PIOD) 是嗅觉丧失的常见原因,治疗选择有限.
嗅觉训练 (OT) 是PIOD的一种有前途的治疗方法,但最佳的训练方案需要进一步研究.

研究的目的:

为了比较一个8气味嗅觉训练 (OT) 方案与PIOD的经典4气味方案的有效性.
评估两种OT方案之间的心理物理嗅觉测试结果和嗅觉球体 (OB) 体积.

主要方法:

一项前性队列研究,涉及72名PIOD患者.
患者被分配到一个4气味 (COT) 或8气味 (EOT) 的OT方案,持续16周.
用Sniffin'Sticks测试评估嗅觉功能,并通过MRI测量患者的一个子集的OB体积.

主要成果:

在4气味和8气味OT组之间没有观察到嗅觉测试结果或OB体积的显著差异.
凸的嗅球 (OB) 患者在治疗后表现出更好的测试结果和改善,无论OT类型如何.
与4气味组相比,8气味的OT组表现出明显更高的坚持率.

结论:

在OT中的气味数量不会显著影响PIOD的治疗疗效.
一个扩展的OT方案 (8种气味) 可以改善患者长期嗅觉康复的坚持.
嗅觉球形状可以作为临床嗅觉功能障碍评估中的预后指标.

关键词:

嗅觉是一种嗅觉.嗅觉灯泡是一种嗅觉灯泡.塑性是一种可塑性.再生再生再生的过程培训培训培训培训培训

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