对于食道状细胞癌的非内镜查:最近的进展
Xiao Mou1, Zhenglin Peng2, Tao Yin2,3
1School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China. muxiao202203@163.com.
Journal of gastrointestinal cancer
|November 4, 2023
概括
早期发现食道状细胞癌 (ESCC) 是至关重要的. 非内镜查,特别是使用瘤生物标志物,显示了改善早期诊断和降低死亡率的前景.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 生物标志物发现发现
背景情况:
- 食道状细胞癌 (ESCC) 造成严重的健康负担,特别是在中国,因为诊断迟到,死亡率高.
- 有限的早期症状阻碍了及时检测,往往导致晚期诊断.
- 早期查和干预对于降低ESCC发病率和死亡率至关重要.
研究的目的:
- 审查最近的非内镜查方法对食道癌的进展.
- 探索提高ESCC早期检测和诊断的策略.
- 为食道癌预防和控制倡议提供科学基础.
主要方法:
- 对ESCC进行内镜和非内镜查方法的比较.
- 评估各种非内镜方法,包括瘤生物标志物 (自身抗体,循环瘤细胞,循环瘤DNA,外体,血清代谢) 和细胞学.
- 专注于瘤生物标志物的潜力,以便早期检测.
主要成果:
- 内镜查受到其侵入性和高成本的限制.
- 非内镜方法,特别是瘤生物标志物,提供了更容易获得的方法.
- 目前的非内镜查方法需要提高早期ESCC检测的诊断效率和准确性.
结论:
- 非内镜查方法比内镜查食道癌更可取.
- 与ESCC的其他非内镜查技术相比,瘤生物标志物应用显示出更高的潜力.
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