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Updated: Jul 11, 2025

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与血红蛋白病变相关的C2H2指转录因子

Xing Zhang1, Fangfang Xia1, Xiaotian Zhang2

  • 1Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Journal of molecular biology
|November 4, 2023
PubMed
概括

胎儿血球蛋白 (HbF) 表达可以治疗β-血球蛋白乱. 克里斯普尔屏幕识别了控制HbF水平的C2H2指蛋白和DNMT1等调节器,提供治疗潜力.

关键词:
C2H2 指蛋白质 指蛋白质蛋白质-DNA相互作用状细胞疾病是一种状细胞疾病.在β-环球蛋白位点.在β-thalassemia中,

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