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在小儿小肠移植中考虑营养支持
Anita M Nucci1, Kathleen Crim2, Elizabeth King3
1Department of Nutrition, Georgia State University, Atlanta, Georgia, USA.
概括
在小儿肠移植 (ITx) 后优化营养对生长至关重要. 仔细监测和量身定制的支持,包括肠外营养 (PN) 和修改饮食,是应对排斥和吸收不良等挑战的关键.
科学领域:
- 儿科胃肠道学和营养学
- 移植手术和免疫学
背景情况:
- 肠道自主性是管理肠道衰竭的主要目标.
- 肠道移植 (ITx) 是患有难治性肠衰竭的患者的一种拯救生命的选择.
- 移植后的并发症,包括排斥和感染,显著影响儿童的营养状况.
研究的目的:
- 审查有关儿童肠移植后营养要求,状态和支持的医学文献.
- 确定优化这一群体营养结果的关键挑战和策略.
主要方法:
- 关于儿科ITx和营养的现有医学研究的全面文献搜索.
- 综合有关营养需求,常见缺陷和推养策略的数据.
- 分析影响增长和管理并发症的因素.
主要成果:
- 在ITx后的生长受到排斥,感染和脂肪吸收不良的挑战.
- 定期评估和修改营养需求至关重要.
- 建议进行早期的术后亲肠道营养 (PN),然后逐渐提供肠道支持.
- 建议对饮食进行修改,包括限制简单碳水化合物和脂肪.
- 微量营养素缺乏和食物过敏是常见的,需要补充.
结论:
- 在儿科ITx后有效的营养管理需要多学科的方法.
- 密切监测人体测量和微量营养素状况对于及时干预至关重要.
- 量身定制的营养支持策略对于促进生长和预防缺陷至关重要.
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