稀土元素的放射性同位素通过逆相高速逆流色谱分离
Mateusz Dembowski1, Hope E Rasmussen1, John E Rowley1
1Los Alamos National Laboratory, Los Alamos, NM 87545, United States.
Journal of chromatography. A
|November 5, 2023
概括
高速逆流色谱 (HSCCC) 为净化稀土元素 (REE) 放射性同位素提供了一个有希望的替代方案,克服了样品吸附和改善核取证应用的分离等挑战.
科学领域:
- 核化学 核化学 核化学
- 分析化学 分析化学
- 染色学分离 染色学分离
背景情况:
- 传统的阴子交换染色学和HPLC在分离稀土元素 (REE) 放射性同位素方面面临挑战,包括吸附问题和近邻分离的困难.
- 自20世纪50年代以来开发的REE放射性同位素分析规模净化现有方法需要改进,以便用于核取证等应用.
研究的目的:
- 评估高速逆流色谱 (HSCCC) 作为一种用于净化REE元素的新方法,重点关注与核取证相关的裂变产品REE.
- 评估HSCCC在克服放射性同位素净化现有分离技术局限性的有效性.
主要方法:
- HSCCC被用于REE分离,包括与放射性追踪物和裂变产品活动的实验.
- 分数分析采用感应合等离子体原子发射光谱 (ICP-AES) 检测元素纯度和玛射线光谱/β计数检测放射性纯度.
主要成果:
- HSCCC展示了高度可重现的分离配置文件,简化了含放射性同位素的样本的样本处理.
- 欧洲 (Eu) 进入萨马 (Sm) 和 (Tb) 分数的最小转移被观察到,Tb 分数中只有微量 (Y) 污染.
- 在重复分离之间脱污因子的变化突出显示了静止相保留差异的影响.
结论:
- HSCCC显示出显著的潜力,作为一种先进的技术,用于REE放射性同位素的特定任务净化.
- 该研究为优化HSCCC提供了有价值的见解,以改善REE放射性同位素分离和消毒.
- 这项工作标志着HSCCC技术在关键放射性同位素净化需求中的实质性进展.
相关概念视频
Ion-Exchange Chromatography
548
Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
548
Capillary Electrophoresis: Applications
407
Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
407
High-Performance Liquid Chromatography: Elution Process
507
In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...
507
High-Performance Liquid Chromatography: Introduction
2.1K
High-performance liquid chromatography(HPLC), formerly referred to as High-pressure liquid chromatography, is a powerful technique used to separate, identify, and quantify components in complex mixtures. The term "high pressure" refers to using high pressure to push the liquid mobile phase through the tightly packed columns.
In HPLC, two phases play a critical role in the separation process:
In HPLC, two phases play a critical role in the separation process:
2.1K
Size-Exclusion Chromatography
613
In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
Silica particles offer advantages such as rigidity,...
613
Principles Of Column Chromatography
6.9K
The chromatography technique was first invented in 1901 by Michael S. Tswett, a Russian botanist, to separate plant pigments using organic solvents. Further, in 1941, Archer John Porter Martin and R. L. M. Synge modified the technique by packing silica gel into a column. A mixture of amino acids was then separated on the packed column using chloroform and water mixture as the mobile phase. This was the first report on column chromatography. At present, column chromatography is a widely used...
6.9K


