在人口层面分析中,肠道微生物组调节了坚持地中海式饮食,腹部脂肪和C反应蛋白之间的关联
Amy Jennings1, Tilman Kühn2, Nicola P Bondonno3
1Institute for Global Food Security, Queen's University Belfast, Northern Ireland.
The American journal of clinical nutrition
|November 5, 2023
概括
另类地中海饮食 (aMed) 可能会降低腹部脂肪和炎症,肠道细菌如Porphyromonadaceae和Peptostreptococcaceae在这些有益影响中发挥中介作用.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 人类生理学 人类生理学
背景情况:
- 地中海饮食对身体组成的影响各不相同.
- 肠道微生物群对这种饮食模式的影响的影响还不太清楚.
研究的目的:
- 为了研究肠道微生物组的调解作用.
- 分析替代地中海饮食 (aMed) 评分,腹部脂肪和炎症之间的关联.
主要方法:
- 来自北德的基于社区的样本 (n=620).
- 通过16S rRNA基因测序进行肠道微生物组分析.
- 对aMed评分,内脏 (VAT) 和皮下 (SAT) 脂肪组织以及C反应蛋白 (CRP) 的评估.
主要成果:
- 较高的aMed分数与较低的SAT,VAT和CRP水平相关.
- 波尔菲罗蒙达属和Peptostreptococcaceae的丰富性调解了这些关联.
- 适度的酒精摄入量与较低的增值税有关,部分原因是由Oxalobacteraceae和Burkholderiaceae解释的.
结论:
- 特定的肠道细菌,特别是Porphyromonadaceae和Peptostreptococcaceae,可能会调解aMed饮食的好处.
- 这些发现突出了肠道微生物组在饮食和身体组成以及炎症关系中的作用.
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