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药理动力学年龄结构化人口模型用于细胞贩运

Wojciech Krzyzanski1, Robert Bauer2

  • 1Department of Pharmaceutical Sciences, University at Buffalo, 370 Pharmacy Building, Buffalo, NY 14214, USA.

Journal of pharmaceutical sciences
|November 5, 2023
PubMed
概括

这项研究开发了一种年龄结构化的细胞种群模型,以量化药物对免疫细胞贩运的影响. 该模型成功地解释了皮质类固醇管理后血细胞计数的反弹,验证了其在药量分析中的使用.

关键词:
皮质类固醇 (皮质类固醇)免疫反应 (Immune Response) 是一种免疫反应.数学模型 (((s) 的使用.药理动力学/药理动力学 (PK/PD) 建模人口的药学动力学.

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