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通过综合计算方法优先考虑与心血管疾病相关的改变NKX2-5和TBX5结合的变异

Edwin G Peña-Martínez1, Diego A Pomales-Matos1, Alejandro Rivera-Madera2

  • 1Department of Biology, University of Puerto Rico Río Piedras Campus, San Juan, Puerto Rico.

The Journal of biological chemistry
|November 5, 2023
PubMed
概括

研究人员开发了一种计算方法,以精确确定与心血管疾病 (CVD) 相关的遗传变异. 这种方法优先考虑影响转录因子结合的单核酸多态 (SNP),有助于识别导致心血管疾病的突变.

关键词:
这是一种DNA结合蛋白质.心血管疾病心血管疾病计算生物学是计算生物学.基因调节 基因调节 基因调节基因组学就是基因组学.单核酸多态性 (SNP) 是一种单核酸多态性.转录因子是一种转录因子.

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