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Updated: Jul 11, 2025

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TBK1-稳定ZNF268a招募SETD4以甲基化TBK1以提供高效的干扰素信号

Yi Liu1, Wei Yin1, Xianhuang Zeng2

  • 1Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, P.R. China.

The Journal of biological chemistry
|November 5, 2023
PubMed
概括

人类指蛋白ZNF268a在病毒感染时稳定,增强抗病毒干扰素信号传递. 这种蛋白质将SETD4招募到TBK1中,促进复杂的组装和对病毒的宿主防御.

关键词:
在SETD4中,SETD4是SETD4.TBK1 的甲基化.在 ZNF268a 中.天生的免疫的特定物种调节.病毒诱导的干扰素信号传递.

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