在COVID-19患者中嗅觉功能障碍
Feras M Alkholaiwi1, Alhanouf F Altamimi1, Hanan H Almalki1
1From the Department of Otorhinolaryngology-Head and Neck Surgery (Alkholaiwi, Alotaibi), College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Kingdom of Saudi Arabia, from the College of Medicine (Almalki, Almughaiseeb, Alsubaie, Alhijli, Alobaishi), Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Kingdom of Saudi Arabia. (Altamimi) From the Department of Family Medicine (Altamimi), King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia, from the Department of Family Medicine (Alsayahi), King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia, from the Department of Family Medicine (Alqahtani), John Hopkins Aramco Healthcare, Eastern Province, Kingdom of Saudi Arabia, and from the Department of Paediatrics (Agrawal), Gandhi Medical College, MP, India.
嗅觉功能障碍 (OD) 是COVID-19患者的常见症状,影响超过34%的个人. 这种症状经常伴随着味觉功能障碍,可以是2019年新冠肺炎疾病 (COVID-19) 的早期指标.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 嗅觉功能障碍 (OD) 和味觉功能障碍 (GD) 是与2019年冠状病毒疾病 (COVID-19) 相关的已知的症状.
- 了解这些感官功能障碍的患病率对于早期诊断和患者管理至关重要.
研究的目的:
- 在被诊断为COVID-19的个人中确定嗅觉功能障碍 (OD) 的频率.
- 分析COVID-19患者中OD与味觉功能障碍 (GD) 的同时发生情况.
主要方法:
- 使用主要数据库 (PubMed,Scopus,Google Scholar,Web of Science) 进行了一次系统的文献审查.
- 包括的研究是在2020年1月至2021年12月期间以英语出版的,报告了COVID-19患者的OD或OD与GD.
- 分析了来自84篇文章的数据,包括来自27个国家的36903名患者.
主要成果:
- 单独嗅觉障碍的总体患病率为34.60%,与味觉功能障碍相结合,为11.36%.
- 具体的嗅觉功能障碍包括厌氧 (20.85%),缺氧 (5.04%),厌氧或缺氧 (8.88%), (1.84%),幻觉 (0.78%),和高 (0.02%).
- 大多数OD患者 (58.1%) 是女性.
结论:
- 嗅觉功能障碍,有或没有味觉功能障碍,是COVID-19患者经常出现的临床特征.
- 这些感官变化是COVID-19的显著早期指标,有助于临床医生及时诊断.
- 这些发现强调了在疑似COVID-19病例中评估嗅觉和味觉功能的重要性.
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