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Updated: Jul 11, 2025

Rapid Generation of Amyloid from Native Proteins In vitro
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Published on: December 5, 2013

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功能和病理性粉样核糖蛋白组合的冷EM结构

Javier Garcia-Pardo1, Salvador Ventura1

  • 1Institut de Biotecnologia i de Biomedicina (IBB) and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.

Trends in biochemical sciences
|November 5, 2023
PubMed
概括

粉样蛋白由RNA结合蛋白 (如hNRNP) 形成,在细胞功能和疾病中具有双重作用. 低温电磁探测揭示了这些粉样蛋白组合的结构,并提供了对其影响的见解.

关键词:
它们是RNA结合蛋白 (RNA-binding proteins,简称RBPs).粉样蛋白纤维的纤维.功能性粉胺是一种功能性粉胺不同质的核核糖核蛋白 (hnRNP)低复杂度域 (LCDs) 是一个低复杂度域.神经退行性疾病的神经退行性疾病

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