"婴儿胃食道逆流调查问卷修订"的年龄相关正常值
Marinde van Lennep1, Fréderique Lansink2, Marc A Benninga1
1Amsterdam UMC location University of Amsterdam, Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Meibergdreef 9, H7-292, PO Box 22700, 1100 DD, Amsterdam, The Netherlands.
European journal of pediatrics
|November 5, 2023
概括
婴儿胃食道逆流问卷修订 (I-GERQ-R) 的得分在健康婴儿中随着年龄的增长而下降. 以前高得分 (≥16) 在新生儿中很常见,可能不表明GER疾病,需要特定年龄的正常值.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
背景情况:
- 婴儿胃食道逆流问卷修订 (I-GERQ-R) 评估了胃食道逆流 (GER) 的症状.
- 在I-GERQ-R上提出了≥16的值,以区分GER和GER疾病.
- 健康婴儿I-GERQ-R的特定年龄的正常值尚未确定.
研究的目的:
- 在0-24个月的健康婴儿中确定I-GERQ-R的特定年龄的正常值.
- 评估与年龄相关的高I-GERQ-R分数的患病率.
- 评估I-GERQ-R得分与婴儿年龄之间的相关性.
主要方法:
- 使用I-GERQ-R对979名0-24个月龄的健康婴儿进行了横截面调查.
- 没有涉嫌GER疾病的婴儿被排除在外.
- 使用Spearman的相关系数来分析I-GERQ-R得分中的与年龄相关的趋势.
主要成果:
- 所有年龄段的I-GERQ-R得分中位数为6.
- 随着年龄的增加,I-GERQ-R得分显著下降 (rs = -0.569,p < 0.001).
- 5%的婴儿得分≥16,在0-4个月的婴儿中患病率更高 (高达16%);这些得分在16个月后消失了.
结论:
- 通过I-GERQ-R测量出的反流症状,在健康婴儿的头24个月内,随着年龄的增长而减少.
- 在I-GERQ-R上得分≥16不应自动被解释为幼婴GER疾病的迹象.
- 验证I-GERQ-R作为GER疾病的诊断工具,需要使用适合年龄的正常值.
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