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基于多参数MRI的VI-RADS:它可以预测1至5年的膀癌复发吗?

Xiaopan Xu¹, Yiping Huang², Yang Liu¹

¹School of Biomedical Engineering, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, Shaanxi, 710032, People's Republic of China.

European radiology

|November 5, 2023

概括

膀成像报告和数据系统 (VI-RADS) 评分显示了预测膀癌复发的潜力,特别是在第一年内. 然而,随着更长的随访期,它的预测准确性会下降.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

膀癌 (BCa) 复发是一个重大的临床挑战.
准确的手术前预后对于指导治疗和监测策略至关重要.
多参数MRI (mp-MRI) 提供了膀的详细解剖和功能信息.

研究的目的:

评估由mp-MRI获得的膀成像报告和数据系统 (VI-RADS) 评分在预测膀癌复发中的有效性.
评估VI-RADS分数在不同后续间隔 (1-5年) 的预后价值.

主要方法:

对284名病理确认的膀瘤患者的回顾性分析.
两个放射科医生使用VI-RADS系统对mp-MRI扫描进行独立评分.
包括皮尔森相关性,t测试和ROC分析在内的统计分析用于复发预测.

主要成果:

VI-RADS评分表明,在诊断后1-4年内,复发和非复发病例之间存在显著差异 (p <0.05).
与得分为3-5 (p <0.05) 的患者相比,VI-RADS得分为1或2的患者的无复发生存率明显更好 (p <0.05).
预测复发的ROC曲线下的面积从1年后的0.744下降到5年后的0.536.

结论:

在mp-MRI上的VI-RADS评分显示了膀癌复发的术前预后的前景.
随着随访时间的延长,VI-RADS的预测性能下降.
患有VI-RADS评分≥3的患者可能受益于加强术后监测,因为在1-2年内复发的风险更高.

关键词:

卡普兰·梅尔估计的估计.多参数磁共振成像技术预测预后预测预测尿道膀的新生病.

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