视网膜敏感度和视网膜血管输液之间的相关性在异常性视网膜膜剥离后
Michele Nicolai1, Alessandro Franceschi1, Serena De Turris1
1Eye Clinic, Polytechnic University of Marche, via Conca 61, 60126, Ancona, Marche, Italy.
European journal of ophthalmology
|November 6, 2023
概括
异常性视网膜外科手术 (iERM) 显著改善视力和视网膜敏感性. 手术后,斑点中的血管 perfusion 密度增加与更好的视觉功能恢复有关.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜成像 视网膜成像
- 外科手术的结果
背景情况:
- 异形性视膜膜 (iERM) 可能导致视力损伤.
- 了解iERM手术后的解剖和功能变化至关重要.
研究的目的:
- 评估iERM手术后解剖和功能变化之间的相关性.
- 评估视网膜敏感度和iERM剥离后的血管 perfusion 密度之间的关系.
主要方法:
- 对接受iERM剥离的患者进行前性,观察性,单中心研究.
- 使用微观测量对最佳校正视敏度 (BCVA),视网膜敏感度 (RS) 和固定稳定性的术前和术后评估.
- 通过SD-OCT和OCTA进行斑点结构分析,包括血管 perfusion 密度 (VPD) 和毛细血管自由区 (CFZ) 面积.
主要成果:
- 在BCVA,RS和固定中显著的术后改善 (p<0.001).
- 与健康的眼睛相比,手术前VPD和CFZ区域的减少 (p<0.05).
- 在手术后增加胆囊膜体外皮层 (choriocapillaris VPD) (p<0.02),在改善的RS组 (p<0.05) 显著增加了表面,深层和胆囊膜体外皮层 (choriocapillaris VPD).
结论:
- 在iERM手术后6个月,视网膜区域的血管 perfusion 密度 (VPD) 较高,视网膜敏感性得到改善.
- 在iERM患者的视觉功能和视网膜输液之间显示出强烈的联系.
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