基于石墨烯的生物传感器用于检测冠状病毒:简要的回顾
Filimon Hadish Abrha1,2, Tadele Hunde Wondimu2,3, Mebrahtu Hagos Kahsay4,5
1Department of Chemistry, College of Natural and Computational Sciences, Aksum University, Aksum 1010, Ethiopia.
Nanoscale
|November 6, 2023
概括
本综述探讨了基于石墨烯的生物传感器,以快速,经济高效地检测SARS-CoV-2. 这些先进的传感器为诊断病毒提供了高灵敏度和选择性,使得点的护理应用.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
背景情况:
- 由SARS-CoV-2引起的全球COVID-19大流行,需要快速和负担得起的诊断工具.
- 生物传感器为检测生物分子提供了一个有前途的途径,石墨烯表现出独特的特性,提高了灵敏度和选择性.
研究的目的:
- 审查用于检测SARS-CoV-2的基于石墨烯的生物传感器技术.
- 讨论这些生物传感器的表面修饰,固定化策略,灵敏度和检测极限 (LOD).
- 以突出使用便携式设备检测SARS-CoV-2的治疗点 (POC) 检测的潜力.
主要方法:
- 关于基于石墨烯的电化学生物传感器的文献综述.
- 关于基于石墨烯的场效应晶体管 (FET) 生物传感器的文献综述.
- 关于基于石墨烯的表面等离子体生物传感器的文献综述.
主要成果:
- 石墨烯的物理,光学和电化学特性适合开发超敏感和选择性的SARS-CoV-2生物传感器.
- 对各种基于石墨烯的生物传感器类型的表面修饰,固定,灵敏度和LOD的细节进行了分析.
- 该审查涵盖了电化学,FET和表面等离子体共振 (SPR) 生物传感器配置.
结论:
- 基于石墨烯的生物传感器显示出用于准确和快速检测SARS-CoV-2的巨大潜力.
- 传感器技术的进步正在为便携式诊断解决方案铺平道路.
- 对表面功能化和设备集成的进一步研究对于临床翻译至关重要.
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