能量负载对人类能量和营养吸收率以及肠道微生物群的影响:一个随机交叉试验
Eiichi Yoshimura1,2, Yuka Hamada1, Yoichi Hatamoto1,2
1Department of Nutrition and Metabolism, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health, and Nutrition, Osaka, Japan.
Obesity (Silver Spring, Md.)
|November 6, 2023
概括
饮食能量摄入量的短期变化动态改变了肠道微生物群的组成. 过度养会通过尿液和便减少能量分泌,但不仅仅是通过便.
科学领域:
- 人类肠道微生物组研究研究
- 营养代谢研究 营养代谢研究
背景情况:
- 肠道微生物群的组成受到饮食能量摄入的影响.
- 了解能量恒温包括评估营养分泌途径.
研究的目的:
- 研究不同能量负载对肠道微生物群的影响.
- 在不同的饮食条件下量化能量和营养分泌率.
主要方法:
- 随机交叉饮食干预与过度养,控制和营养不良的条件.
- 评估肠道微生物群的组成 (α-多样性,类,属).
- 通过便和尿液测量能量排泄,使用炸弹热量计.
主要成果:
- 短期的能量负载显著改变了肠道微生物群的多样性和组成.
- 通过尿液和联合尿-便的能量分泌在过度养下较低,相比之下,对照和营养不良.
- 便能量分泌率不受饮食能量负载变化的影响.
结论:
- 短期过度养会影响肠道微生物群的组成.
- 在过度养期间观察到尿液和便能量分泌量的减少.
- 便能量分泌不是短期饮食能量负载变化的敏感指标.
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