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Updated: Jul 11, 2025

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结合激活WNT-依赖的纤维基因子程序通过不同的补充子单元在衰变肌肉的组合激活

Francesca Florio1,2,3, Sara Vencato1,2, Filomena T Papa1,2

  • 1Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.

EMBO molecular medicine
|November 6, 2023
PubMed
概括

杜氏肌肉发育不良 (DMD) 中的纤维化涉及补体和WNT通路之间的交叉通话. 在小鼠中抑制补充C1r / s减少了WNT激活和改善肌肉功能,提供了新的治疗策略.

关键词:
杜申尼肌肉发育不良症 杜申尼肌肉发育不良症补充 C1 复合体的复合体.纤维基原始体的原始体.纤维化 纤维化骨肌肉的再生和再生

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