在患有固体瘤的瘤患者中预后因素,需要在重症监护室入院
Raquel Bosch-Compte1, Laura Visa2,3, Alejandro Rios2
1Department of Critical Care Medicine, Hospital del Mar, 08003 Barcelona, Spain.
Oncology letters
|November 6, 2023
概括
这项研究确定了预测进入重症监护室 (ICU) 的癌症患者死亡率的关键因素. 结果强调了序列器官衰竭评估 (SOFA) 评分和中性质减退作为癌症患者生存的关键预测因素.
科学领域:
- 在瘤学瘤学.
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 进入重症监护室 (ICU) 的癌症患者面临高死亡风险.
- 了解死亡率和长期结果的预测因素对于改善患者护理至关重要.
研究的目的:
- 为了确定预测癌症患者入院医疗ICU的住院死亡率的因素.
- 评估这些患者在出院后的最初12个月的功能状态和生存率.
主要方法:
- 对129名连续癌症患者的回顾性观察性研究,这些癌症患者患有固体瘤,被送往医疗ICU.
- 收集的数据包括人口统计,临床信息,ICU和住院死亡率以及出院后的随访.
主要成果:
- 在ICU和医院的死亡率分别为24%和40.3%.
- 对于ICU死亡的独立风险因素包括更高的顺序性器官衰竭评估 (SOFA) 评分,中性贫血,转移性疾病和侵入性机械通风.
- 入院期间的手术和更长的ICU停留 (>48小时) 与较低的死亡率有关.
- 59.5%的幸存者在出院时具有良好的功能状态,28.7%在出院1年后还活着,大多数具有良好的功能状态.
结论:
- 在接受ICU治疗的癌症患者的住院死亡率与SOFA得分,机械通风的需要,中性衰竭和转移性疾病有关.
- 幸存者的很大一部分在出院时和出院后的一年内达到良好的功能状态.
- 这些发现可以为危急癌症患者的风险分层和管理策略提供信息.
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