通过BACTEC MGIT 960培养诊断结核病的临床标本中的组织病理特征
Nguyen Kim Cuong1,2, Dang Van Thanh3, Dinh Van Luong4
1Department of Respiratory Tuberculosis, National Lung Hospital, Hanoi, Vietnam.
Journal of clinical tuberculosis and other mycobacterial diseases
|November 6, 2023
概括
在高负担的国家,诊断肺外结核 (TB) 是很困难的. 组织病理学,特别是上皮细胞,朗汉斯巨细胞和病变性亡,强烈表明活检样本中的结核病,有助于诊断.
科学领域:
- 病理学 病理学 病理学
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- 肺外结核 (TB) 诊断在中低收入国家具有挑战性.
- 准确的诊断方法对于有效的结核病管理至关重要.
研究的目的:
- 描述已确认结核病患者的活检样本中的组织学特征.
- 评估组织病理学在诊断肺外结核病中的有用性.
主要方法:
- 临床活检样本的回顾性研究.
- 样本被培养为 * Mycobacterium 结核病 * 并接受了他的病理学检查.
- 分析了培养基的阳性率和常见的组织学发现.
主要成果:
- 总体而言, * Mycobacterium tuberculosis * 培养物的阳性是20.7%.
- 培养阳性因样本类型而异 (例如,骨75%,淋巴结26.3%).
- 表皮状细胞 (83.3%),朗汉斯巨细胞 (75.9%) 和病变性亡 (75.5%) 是培养确认结核病的常见组织学发现.
结论:
- 组织学特征在培养确认的活检样本中高度暗示着结核病.
- 组织学检查,结合分子分析,可以改善肺外结核病诊断.
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