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感觉神经动作潜在幅度和速度与2型糖尿病外围神经病变的关联

Anwar H Siddiqui¹, Nazia Tauheed², Hamid Ashraf³

¹Physiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, IND.

|November 6, 2023

概括

糖尿病外围神经病变与神经信号幅度的减少有关. 感官神经动作潜力和速度显示为糖尿病患者这种情况的早期指标.

科学领域:

神经学神经学
糖尿病学糖尿病学
临床电生理学临床电生理学

背景情况:

糖尿病外围神经病变 (DPN) 诊断是有争议的,关于脱髓化与轴突退化的不确定性作为主要神经损伤.
了解潜在的病理生理学对于有效的DPN管理至关重要.

研究的目的:

调查神经传导研究 (NCS) 参数与DPN之间的关联.
评估神经传导速度 (NCV) 和动能振幅作为DPN的早期指标.

主要方法:

一项横截面研究包括220名2型糖尿病患者 (症状和无症状DPN) 和100名健康对照.
进行了NCS,包括上肢和下肢 (中部,后部部,外围神经) 的运动和感觉研究.

主要成果:

与对照组相比,糖尿病患者表现出明显较低的感觉神经动作潜力 (SNAP) 和复合肌肉动作潜力 (CMAP) 幅度.
在61.36%的糖尿病患者中发现了神经传导异常,最常发生在外围神经中.
减少SNAP振幅是最常见的异常,其次是减少NCV.

结论:

减少的SNAP振幅与糖尿病外围神经病变有关.
NCS参数,特别是SNAP和NCV,是检测糖尿病患者周围神经病变的敏感指标.

关键词:

动作潜力的幅度动作潜力的幅度糖尿病周围神经病变早期诊断早期诊断早期诊断运动神经的运动神经.神经传导研究神经传导研究感觉神经是感觉神经.

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