在COVID-19中急性四肢缺血:系统性审查
Suci Indriani1,2, Mohamed Amshar1, Raka Aldy Nugraha3
1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
概括
冠状病毒疾病2019 (COVID-19) 与急性四肢缺血症 (ALI) 相关,原因是高凝固性. 在COVID-19患者中,急性肢体缺血表明预后不佳,死亡率和截肢率高.
科学领域:
- 血管外科 血管外科
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 与急性四肢缺血症 (ALI) 的发生率增加有关.
- 了解COVID-19患者ALI的临床特征和结果对于有效管理至关重要.
研究的目的:
- 分析COVID-19患者急性四肢缺血的临床特征,治疗策略和结果.
- 调查COVID-19严重程度与ALI发展之间的关系.
主要方法:
- 在PubMed,ScienceDirect和Cochrane数据库中进行了系统的文献搜索.
- 从56篇文章中提取和分析了191名受试者的数据,重点是ALI位置,COVID-19严重程度,并发症,实验室参数,治疗和结果.
- 两个独立审稿人汇集数据.
主要成果:
- 大多数ALI病例 (94.2%) 是新发病,主要影响下肢 (82.7%),特别是尾动脉 (48.2%).
- 严重的COVID-19在38.1%的患者中存在;升高的D-二次体 (98.1%) 和C-反应蛋白 (83.3%) 是常见的.
- 观察到高整体死亡率 (39.3%) 和四肢截肢率 (22.4%),呼吸衰竭是死亡的主要原因 (67.6%).
结论:
- COVID-19与高凝血相关,这可能会导致急性四肢缺血症.
- 急性四肢缺血是COVID-19患者不良结果的潜在指标.
- 在COVID-19中迅速识别和管理ALI至关重要,以改善患者的生存和肢体救援.
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