妊娠期热囊细胞疾病与同时存在的进展性怀孕:个性化治疗方式
Elena Ulrikh1, Elena Dikareva1, Igor Govorov1
1Personalized Medicine Center, Almazov National Medical Research Centre, Saint-Petersburg 197341, Russia.
International journal of clinical practice
|November 6, 2023
概括
与怀孕同时存在的妊娠热囊细胞疾病 (GTD) 是罕见的. 本研究详细介绍了五个病例,并提出了对这种高风险疾病的管理策略,强调了多学科的护理和监测.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 在瘤学瘤学.
背景情况:
- 与正在进展的怀孕同时存在的妊娠热囊细胞疾病 (GTD) 是非常罕见的.
- 文献主要包括孤立的案例报告或详细介绍成功分娩的小案例系列.
研究的目的:
- 描述五例与稳步进展的怀孕并存的GTD病例.
- 介绍这种罕见的产科并发症的潜在管理策略.
主要方法:
- 五个怀孕同时存在GTD的临床数据的回顾性审查.
- 数据是在2018年至2021年期间从阿尔马佐夫国家医学研究中心收集的.
主要成果:
- 包括三次多胎妊娠与完整的水性形子和两次单胎怀孕与胆管癌或侵入性子.
- 60%的GTD病例显示恶性转变.
- 三次怀孕导致过早分娩;新生儿经历过早产,不成熟和贫血.
结论:
- 患有GTD的孕妇面临早产,流产,出血和疾病进展的风险.
- 管理需要一个多学科的团队经验,在怀孕期间管理恶性瘤.
- 推的监测包括连续成像,胎儿测试和每周的β-hCG评估,以及特定的产后随访.
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