在怀疑结肠分管出血的患者中,对于早期结肠镜检查,是否需要进行肠道准备? :一个多中心的回顾性研究与倾向性得分匹配分析
Takahiro Gonai1,2, Yosuke Toya1, Norihiko Kudara3
1Division of Gastroenterology and Hepatology Department of Internal Medicine Iwate Medical University School of Medicine Iwate Japan.
DEN open
|November 6, 2023
概括
在怀疑结肠管出血 (CDB) 的患者中,用于早期结肠镜的聚乙烯糖醇洗 (PEL) 制剂显著减少了住院时间,并改善了管输管率. 在接受紧急结肠镜检查的CDB患者中,对于更好的结果,可能更喜欢PEL.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 结肠直肠手术 结肠直肠手术
背景情况:
- 结肠分管出血 (CDB) 是下胃肠道出血的常见原因之一.
- 在CDB患者中,为早期结肠镜检查做好最佳肠道准备并未得到充分证实.
- 很少有研究研究了特定肠道制剂对CDB结肠镜检查结果的影响.
研究的目的:
- 为了评估聚乙烯糖醇洗 (PEL) 在接受早期结肠镜检查怀疑CDB的患者的肠道准备的有效性.
- 为了比较PEL准备的患者和没有PEL的患者之间的结果.
主要方法:
- 这是一项回顾性,多中心的队列研究,涉及10所机构.
- 在接受早期结肠镜检查 (24小时内) 的疑似CDB患者中,分析临床特征和结肠镜检查结果.
- 使用倾向性得分匹配,比较接受PEL和不接受PEL的患者之间的结果.
主要成果:
- 接受PEL治疗的患者年龄较小,并发病率较少,表现状况更好.
- 在倾向得分匹配后,PEL组的住院时间显著缩短 (7.9 vs 10.1天) 和腔输管率更高 (91.1% vs 50.0%).
- 在不良事件,最近出血的污名的识别或内镜静血治疗频率方面没有发现显著差异.
结论:
- 聚乙烯糖醇洗 (PEL) 制剂与怀疑结肠管出血的患者早期结肠镜检查的改善结果有关.
- 在这种特定的临床场景中,PEL可能是首选的肠道制备方法,以提高结肠镜效率和患者康复.
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