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Updated: Jul 11, 2025

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通过整体机器学习预测性结肠炎患者的抗TNF治疗失败:一项前性研究

Mohammad Hossein Derakhshan Nazari1, Shabnam Shahrokh2, Leila Ghanbari-Maman1,3

  • 1Basic and Molecular Epidemiology of Gastrointestinal Disorders, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Heliyon
|November 6, 2023
PubMed
概括

这项研究确定了对抗TNF治疗不反应的性结肠炎 (UC) 患者的关键基因和免疫细胞变化. 一个新的五个mRNA小组准确地预测了非响应者,使UC治疗的个性化药物成为可能.

关键词:
抗TNF疗法是一种治疗方法.生物标志物生物标志物整合机器学习 机器学习炎症 炎症是一种炎症.炎症性肠病是一种炎症性肠病.性结肠炎是一种

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