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Blood and Nerve Supply to the Kidney01:18

Blood and Nerve Supply to the Kidney

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The kidneys are vital organs responsible for filtering and cleaning blood, removing waste products, and regulating electrolyte levels. To perform these essential functions, they require a constant and robust blood supply.
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
1.1K
Nephrons01:10

Nephrons

2.6K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.6K
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration01:29

Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration

27
The kidneys are vital organs responsible for regulating blood filtration, waste excretion, and fluid balance, all of which are crucial for maintaining homeostasis. Renal physiology examines renal blood flow, glomerular filtration, and urine formation, ensuring the body’s internal environment remains stable.Renal Blood FlowThe kidneys receive about 20-25% of the cardiac output, typically around 1200 mL of blood per minute in an average adult. Blood flows into the kidneys through the renal...
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Filtration and Urine Formation01:32

Filtration and Urine Formation

50.1K
The function of the kidneys is to filter, reabsorb, secrete, and excrete. Every day the kidneys filter nearly 180 liters of blood, initially removing water and solutes but ultimately returning nearly all filtrates into circulation with the help of osmoregulatory hormones. This process removes wastes and toxins but is also crucial to maintain water and electrolyte levels. Most of these functions are performed by the tiny but numerous nephrons contained within the kidneys.
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Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion01:22

Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion

32
The kidneys maintain homeostasis through filtration, reabsorption, and secretion. Tubular reabsorption and secretion are crucial in forming urine and regulating electrolytes, water balance, and waste elimination.Tubular Reabsorption and Secretion ProcessesTubular reabsorption is the process that reclaims essential substances such as electrolytes, glucose, amino acids, and water from the glomerular filtrate back into the bloodstream. This is achieved through passive and active transport...
32
Kidney Structure01:45

Kidney Structure

69.8K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
69.8K

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相关实验视频

Updated: Jul 11, 2025

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells
05:35

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells

Published on: September 28, 2022

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在脏动脉网络上相互作用的信息流.

Donald J Marsh1, Anthony S Wexler2, Niels-Henrik Holstein-Rathlou3

  • 1Department of Medical Sciences, Division of Medicine and Biological Sciences, Brown University, Providence, RI, United States.

Frontiers in network physiology
|November 6, 2023
PubMed
概括

脏的血流通过相互作用的肌源性和管状球体反机制来调节. 这些机制同步相邻的脏,但不是远处的脏,影响功能.

关键词:
动脉网络是动脉网络的组成部分.边界的边界边界的边界肌原性机制的产生机制尼弗朗集群是尼弗朗集群.部分同步的部分同步.脏自我调节的发生.时间同步同步同步同步.管球体球体反的反

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Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats
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Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats

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Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
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Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

Published on: June 27, 2015

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相关实验视频

Last Updated: Jul 11, 2025

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells
05:35

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells

Published on: September 28, 2022

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Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats
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Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats

Published on: February 8, 2022

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Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
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Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

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科学领域:

  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 生理学 生理学 生理学
  • 计算生物学 计算生物学

背景情况:

  • 功能依赖于复杂的血液流动和过的调节.
  • 两个主要机制 - - 肌源性反应和管球体反 (TGF) - - 控制着 afferent arteriole 的功能.
  • 这些机制作为合振荡器,影响脏血动力学.

研究的目的:

  • 模拟肌源性和TGF机制在调节脏血流中的相互作用.
  • 调查动脉网络内的相邻和非相邻脏的同步模式.
  • 通过对压力和流量振荡的实验数据验证模型.

主要方法:

  • 在树状动脉网络中开发了10个脏和它们的 afferent arterioles 的计算模型.
  • 模拟的相互作用包括TGF-myogenic合,相邻和非相邻的脏合,以及动脉压力合.
  • 动脉网络的内置结构特征,包括表面和地下组成部分.

主要成果:

  • 该模型成功地重现了对脏同步的实验结果,显示了相邻的脏之间完全的同步以及非相邻的部分同步.
  • 模拟预测了管道和动脉压力的非周期性波动,与观察到的数据一致.
  • 该模型表明,没有实现所有神经元的完整同步.

结论:

  • 肌源性和TGF机制的相互作用驱动了脏血液动力学中复杂的振荡行为.
  • 通过动脉壁传输的电信号促进了同步,主要是在相邻的脏之间.
  • 开发的模型为了解自身调节和网络动态提供了有价值的工具.