痴呆症在4级大学中心的患病率:问题有多大?
Christoph Helmstaedter1, Teresa Lutz1, Vinzent Wolf1
1Department of Epileptology, University Hospital Bonn (UKB), Bonn, Germany.
Frontiers in neurology
|November 6, 2023
概括
在专门中心的患者中,痴呆的患病率很低. 然而,老年和晚发性会增加痴呆症的风险,发作可能是神经退行性疾病的信号.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 老年病的医生 老年病的医生
背景情况:
- 和痴呆症之间的联系是一个重要的研究领域.
- 了解患者痴呆症患病率对于综合护理至关重要.
研究的目的:
- 调查一个大型大学中心内痴呆症诊断的流行率.
- 在患者中确定与痴呆相关的危险因素.
主要方法:
- 追溯分析来自40360名成年患者的145501封医疗信件 (2003-2021年).
- 搜索与痴呆相关的术语并分析患者数据,包括年龄,发病和诊断时间.
- 确定了并发症,并评估了和痴呆症之间的时间关系.
主要成果:
- 在513名患者中发现了与痴呆相关的术语;12.7%的人被诊断为痴呆症.
- 在所有患者中,确诊或疑似痴呆的总体患病率为0.25%.
- 高龄 (≥60) 和晚发性 (≥60) 显著增加了痴呆的几率 (分别是6.1倍和2.9倍).
- 通常在痴呆症诊断之前发生 (23.2%对8.1%).
- 常见的并发症包括血管,代谢,炎症和情绪相关的疾病.
结论:
- 这种中心队列中痴呆症的患病率相对较低,但医生必须考虑老年患者和晚发患者的风险增加.
- 发作可能是潜在神经退行性疾病的早期指标.
- 需要进一步的研究来查患者的痴呆症,并按病理和并发症分层.
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