在Omicron浪潮期间,COVID-19儿童的发烧发作
Pu Xu1, Xuelian Chen2, Jianguo Zhou1
1National Health Commission Key Laboratory of Neonatal Diseases, Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
Frontiers in pediatrics
|November 6, 2023
概括
发烧性发作可能是COVID-19儿童的主要神经症状,即使没有先前的,也会出现. 这种情况与严重疾病无关,但长期的神经结果需要监测.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19在儿童中呈现出各种神经学表现.
- 发烧性发作在儿童时期很常见,但它们与COVID-19的关联需要进一步调查.
研究的目的:
- 研究儿童COVID-19患者发烧的临床特征和预后.
- 为了比较COVID-19患者与没有发烧之间的临床特征和结果.
主要方法:
- 一个单一中心的回顾性队列研究包括585名COVID-19儿童.
- 临床数据,发作表现,COVID-19严重程度和SARS-CoV-2核酸测试结果进行了比较.
- 发烧发作的儿童接受了一个月的随访.
主要成果:
- 15名儿童 (1.8%) 经历过发烧性,主要是泛性增强性-克隆性.
- 两组之间没有观察到性别,COVID-19严重程度或临床表现的显著差异 (不包括潜在疾病).
- 发现了显著的年龄差异 (2年对1.3年,P=0.047),病毒清除时间没有差异.
结论:
- 发烧性发作可能是儿童COVID-19的主要神经学表现.
- 这些发作可以发生在没有史的儿童身上,并且与严重的COVID-19疾病无关.
- 建议对受影响的儿童进行长期神经学随访.
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