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Updated: Jul 11, 2025

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
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针对树突细胞-T细胞轴,开发针对质母细胞瘤的有效免疫疗法

Bryan Gardam1,2, Tessa Gargett1,2,3, Michael P Brown1,2,3

  • 1Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia.

Frontiers in immunology
|November 6, 2023
PubMed
概括

由于瘤微环境和血脑屏障,质母细胞瘤免疫疗法面临着挑战. 与T细胞策略一起增强树突细胞功能可能会改善质母细胞瘤治疗结果.

关键词:
在CAR-T细胞中.在T细胞,T细胞.大脑瘤是个大脑瘤癌症 癌症 癌症 癌症 癌症组合疗法 组合疗法树突细胞是一种树突细胞.质母细胞瘤 (glioblastoma) 是一种免疫疗法 免疫疗法

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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