在正常认知和轻度认知障碍中,客观睡眠质量和数量以及口头记忆表现之间的长期关联
Eleni Skourti1, Panagiotis Simos1,2,3, Alexandros Zampetakis1
1Division of Psychiatry and Behavioral Sciences, School of Medicine, University of Crete, Heraklion, Greece.
Frontiers in neuroscience
|November 6, 2023
概括
良好的睡眠质量直接改善老年人的记忆功能,而更长的睡眠时间可能间接地损害它,特别是在那些有轻度认知障碍 (MCI) 的人群中. 改善睡眠可以帮助预防记忆力下降.
科学领域:
- 老年学是指老年学的学科.
- 睡眠科学 睡眠科学
- 认知神经科学 认知神经科学
背景情况:
- 睡眠与记忆之间的关系已经确立,但其在正常认知和轻度认知障碍 (MCI) 中的具体情况需要进一步调查.
- 了解睡眠宏观结构如何影响长期记忆对于老年人群至关重要.
研究的目的:
- 检查客观测量的睡眠质量,持续时间和床上的时间与7-9年的口头记忆能力之间的纵向关联.
- 为了区分这些协会在认知无障碍 (CNI) 个人和那些有MCI.
主要方法:
- 来自克里特老龄化队伍的148名参与者 (79名MCI,69名CNI,平均年龄为72.8岁) 通过3天的动图进行了睡眠评估.
- 在基线和随访时,使用Rey听觉语言学习测试 (RAVLT) 和希腊经文记忆测试来评估语言记忆.
- 使用面板模型来分析数据,控制相关的共变量.
主要成果:
- 基线睡眠效率直接预测了即时和延迟回忆任务中的后续记忆性能.
- 在睡眠开始后醒来直接预测了即时通道回忆,在MCI组中显著.
- 更长的24小时睡眠时间和卧床时间间接与记忆能力的降低有关,主要在MCI组.
结论:
- 睡眠质量差和睡眠时间延长与老年人的记忆功能恶化有关.
- 旨在改善睡眠的干预措施可能在预防或延缓与年龄相关的记忆力下降方面发挥作用.
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