在结肠镜检查期间比较低体积与常规体积的聚乙烯糖醇用于肠道准备:一项随机对照试验
Muhammad Faeid Othman1,2,3, Andee Dzulkarnaen Zakaria1,2,3, Maya Mazuwin Yahya1,2,3
1Department of Surgery, School of Medical Science, Universiti Sains Malaysia, Kelantan, Malaysia.
The Malaysian journal of medical sciences : MJMS
|November 6, 2023
概括
低容量 (2L) 聚乙烯甘醇 (PEG) 肠道准备与标准的3L PEG对结肠镜一样有效. 这项研究发现,这两个体积之间的肠道清洁性或耐受性没有显著差异.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 药理学 药理学是指药理学的学科.
背景情况:
- 聚乙烯甘醇 (PEG) 溶液是一种标准的结肠镜肠道制备剂.
- 大量的PEG溶液可能导致患者的耐受性和服从性较差.
- 低量PEG溶液可以改善患者的体验和坚持.
研究的目的:
- 为了比较低容量 (2L) PEG溶液与常规 (3L) 容量的有效性,用于在结肠镜检查前的肠道准备.
- 评估肠道清洁,结肠镜检查的完整性,患者耐受性和手术持续时间的差异.
- 为了确定减少PEG体积是否会影响结肠镜检查结果.
主要方法:
- 一项前性,随机的,单盲的受控研究,涉及164名接受结肠镜检查的患者.
- 患者被分配接受3L (控制) 或2L (干预) 的PEG溶液.
- 用波士顿肠道准备量表 (BBPS) 评估肠道清洁度;还记录了结肠镜检查的完整性,耐受性和持续时间.
主要成果:
- 在2L和3L PEG组之间,在肠道清洁度 (P=0.119) 中没有观察到统计学上显著的差异.
- 患者耐受性 (P=0.190) 和结肠镜完成率 (P=0.535) 在两组中都相似.
- 结肠镜检查的持续时间在低体积PEG组明显较短 (P=0.039).
结论:
- 低容量 (2升) PEG溶液是标准3升容量的有效替代品,用于在结肠镜检查前进行肠道准备.
- 在肠道清洁和耐受性方面的有效性在两卷之间是可比的.
- 可能需要进一步的研究来确定PEG体积的优越性.
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