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Bin Yang¹, Qingsong Lai², Aiqi Chen²

¹Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou City, Guangdong, 510091, People's Republic of China.

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|November 6, 2023

概括

儿童肥胖与皮肤屏障功能的改变有关,特别是在男孩身上. 皮肤水分和pH与男孩的体重指数 (BMI) z分数相关,这表明儿童肥胖和表皮健康之间存在联系.

科学领域:

皮肤病学皮肤病学
儿科儿科儿科
公共卫生公共卫生

背景情况:

在各种疾病中观察到表皮功能变化.
儿童肥胖是一个日益严重的公共卫生问题,具有潜在的系统性影响.

研究的目的:

为了研究体质指数 (BMI) z分数和儿童表皮功能之间的关系.
评估与儿童肥胖相关的特定表皮生物物理特性.

主要方法:

从门诊,学校和幼儿园招募儿童.
测量了表皮层生物物理特性,包括跨皮层水损失 (TEWL),角层水分和皮肤表面pH值.
分析了这些属性与BMI z分数之间的相关性.

主要成果:

在男孩中,BMI z分数与角层水分的负相关性,与皮肤表面pH的正相关性,但在女孩中没有.
与平均BMI z分数 (-2至0.99) 相比,具有较高BMI z分数 (≥2) 的男孩的角质层水分水平显着较低.
在TEWL和BMI z分数之间没有发现显著的相关性.

结论:

儿童肥胖与表皮功能变化有关,特别是男孩的角层水分减少和皮肤表面pH值增加.
这些发现表明表皮健康和儿童肥胖之间存在潜在联系,尽管这种关系的方向性需要进一步调查.

关键词:

体重指数 (BMI) z分数得分身体质量指数 (BMI) 是指身体质量指数.皮肤表面pH值皮肤表面pH值层状角膜的水合化通过皮肤的水损失.

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