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肝炎状况及其对慢性病进展的影响:表现,关联和并发症
Shamsa AlMaawali1, Issa Al Salmi2, Ahmed Al-Darmaki3
1Department of Medicine, Royal Hospital, Muscat, Oman.
概括
在阿曼,慢性病 (CKD) 与病毒性肝炎 (乙型肝炎病毒和型肝炎病毒) 有着显著的关联. 肝炎C病毒感染显示CKD患病率最高,强调需要对功能进行监测.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肝病学 肝病学是一种肝病学.
- 流行病学 流行病学
背景情况:
- 慢性病 (CKD),乙型肝炎病毒 (HBV) 和乙型肝炎病毒 (HCV) 在阿曼普遍存在.
- 已经建议病毒性肝炎和CKD风险之间存在显著的关联.
研究的目的:
- 在阿曼调查CKD和病毒性肝炎 (HBV和HCV) 之间的关联.
- 为了评估慢性HBV,慢性HCV和HBV/HCV共感染的患者中CKD的患病率.
主要方法:
- 在阿曼苏丹王国皇家医院进行了一项观察性队列研究.
- 分析了233名患者:112名患有慢性HBV,112名患有慢性HCV,9名患有共感染.
- 对每组计算了CKD的患病率和平均估计的球过率 (eGFR).
主要成果:
- 在HBV中,CKD患病率为51%,在HCV中为78%,在共感染组中为56%.
- 同感染组的平均EGFR最低 (57.6毫升/分钟/1.73米2).
- 感染HCV的CKD患病率最高,功能下降速度最快.
结论:
- 病毒性肝炎,特别是HCV感染和共感染,显著且独立地与慢性病风险增加有关.
- 密切监测功能对于病毒性肝炎患者至关重要.
- 对于被诊断患有CKD的患者,建议对病毒性肝炎进行查.
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