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Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis
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骨髓细胞衍生IL1β有助于HFpEF中的肺高血压

Vineet Agrawal1,2, Jonathan A Kropski3, Jason J Gokey3

  • 1Division of Cardiovascular Medicine (V.A., E.K., K.T.M., D.F.M., K.M., Y.R.S., D.K.G.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

Circulation research
|November 6, 2023
PubMed
概括

心力衰竭中的肺高血压与保存的喷射分数 (PH-HFpEF) 是由髓质细胞衍生的IL-1β驱动的. 在小鼠中减少IL-1β可以防止PH和血管重塑在HFpEF模型中.

关键词:
细胞因子 细胞因子心脏衰竭是因为心脏衰竭.高血压,肺部高血压,肺部高血压.巨细胞是什么?巨细胞是什么?骨髓状细胞是骨髓状细胞.

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