澳大利亚中部偏远地区的土著和非土著澳大利亚人心力衰竭
Manoj Rajamohan1,2, Zaheeruddin Jayhoon1, Benjamin Gomez1
1Alice Springs Hospital, Alice Springs, Northern Territory, Australia.
Internal medicine journal
|November 6, 2023
概括
心力衰竭 (HF) 在澳大利亚中部的澳大利亚土著人中超过两倍,特别是年轻人和女性. 尽管有类似的治疗方法,但土著患者面临更高的重大心血管不良事件 (MACE) 和死亡率.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 土著健康土著健康
背景情况:
- 澳大利亚中部心力衰竭 (HF) 负担的数据有限,该地区有大量土著人口.
- 对于公共卫生倡议来说,了解这一人口群体中的HF患病率和结果至关重要.
研究的目的:
- 在澳大利亚中部诊断出HF的澳大利亚土著和非土著人的特征和比较.
- 为了确定这些群体之间的高频率流行,风险因素和结果的差异.
主要方法:
- 从2019年至2021年,研究了一组424名患有HF和减少喷射分数 (<50%) 的患者队列.
- 收集和分析了临床,心声和主要不良心血管事件 (MACE) 数据.
- 对于原住民和非原住民个人,每1万人口计算出患病率.
主要成果:
- 澳大利亚原住民占HF队列的70%,年龄明显较小 (53岁对68岁).
- 在土著患者中观察到风湿性心脏病,糖尿病和严重慢性病 (CKD) 的更高率.
- 原住民 (138/10,000) 与非原住民 (53/10,000) 澳大利亚人的HF患病率是两倍以上,特别是在年轻女性中.
- 尽管类似的指导方针导向医疗 (GDMT) 吸收,土著患者经历了显著更高的MACE (54%对28%) 和所有原因的死亡率 (24%对13%).
结论:
- 心力衰竭在澳大利亚中部土著人中普遍存在,影响年轻人不成比例.
- 患有HF的本地患者面临更差的结果,包括更高的MACE和死亡率,尽管疾病的原因和医疗管理相似.
- 这些发现突出了关键的差异,并为减少澳大利亚土著人心血管发病率和死亡率差距的战略提供了信息.
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