自我报告的睡眠碎片化和睡眠持续时间以及它们与认知功能的关联在PROTECT中,这是一个50岁以上的大型数字社区群体
Jon Arild Aakre1,2, Jörn Schulz3, Clive Ballard4
1Centre for Age-Related Medicine - SESAM, Stavanger University Hospital, Stavanger, Norway.
International journal of geriatric psychiatry
|November 6, 2023
概括
睡眠不足,包括短暂,长时间或碎片化睡眠,与老年人的认知能力下降有关. 这些睡眠问题可能是维持大脑健康的干预措施的目标.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 睡眠医学 睡眠医学
背景情况:
- 睡眠障碍在老年人中很常见,并对认知功能产生负面影响.
- 保持认知健康对于老龄化人口的生活质量至关重要.
研究的目的:
- 研究50岁以上成年人自我报告的睡眠时间 (短/长) 和睡眠碎片化与认知功能之间的关联.
- 为了确定潜在的睡眠相关的认知衰退风险因素.
主要方法:
- 利用了来自PROTECT研究的8508名参与者的横截面数据.
- 在四个认知结果上使用单变量线性回归分析:视觉空间情节性记忆 (VSEM),空间工作记忆,口头工作记忆 (VWM) 和口头推理 (VR).
主要成果:
- 短 (<6h) 和长 (>9h) 的睡眠时间与较差的VWM显著相关.
- 长时间的睡眠时间与口头推理 (VR) 障碍有关,而短时间的睡眠和睡眠碎片化与减少的VSEM有关.
- 即使考虑到其他认知衰退风险因素,如高血压和抑郁症,这些关联仍然存在.
结论:
- 睡眠时间短,睡眠时间长和睡眠碎片化是认知能力下降的潜在风险因素.
- 针对睡眠质量和持续时间可能为旨在保护老年人认知功能的干预提供策略.
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