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Updated: Jul 11, 2025

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
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在三方体中酶抑制的结构基础E. 大肠杆菌HipBST毒素-抗毒素系统

René L Bærentsen1, Stine V Nielsen2, Ragnhild B Skjerning1

  • 1Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.

eLife
|November 6, 2023
PubMed
概括

大肠杆菌中的HipBST毒素-抗毒素系统使用HipS抑制HipT毒素激酶. HipS通过将托残留物插入其活性部位来阻止HipT的活动,从而揭示了对细菌毒素-抗毒素调节的新见解.

关键词:
美国大肠杆菌 (E. coli).这就是HipBAHipBA.在STK和STK之间.通过Ser/Through酶激酶进行.这里是TrpS.传染病是一种传染性疾病.微生物学的微生物.分子生物物理学分子生物物理学结构生物学结构生物学这是tRNA合成酶.

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